Bone-bonding Organic-inorganic Nanohybrids
　Natural bone is a kind of organic-inorganic hybrid composed of inorganic hydroxyapatite and organic collagen fiber. If inorganic components which achieve bone-bonding ability and organic polymers are combined at nanometer level, novel bone-repairing materials with not only biocompatibility but also mechanical performances highly analogous to the bone can be developed.

Design of Bone-bonding Organic-inorganic Nanohybrids.	Flexible organic-inorganic nanohybrid.

Papers

• T. Miyazaki, M. Imamura, E. Ishida, M. Ashizuka and C. Ohtsuki, "Apatite Formation Abilities and Mechanical Properties of Hydroxyethylmethacrylate-based Organic-inorganic Hybrids Incorporated with Sulfonic Groups and Calcium Ions," J. Mater. Sci. Mater. Med., 20, 157-161 (2009) .
• Y. Morita, T. Miyazaki, E. Ishida and C. Ohtsuki "Apatite-forming Ability of Organic-inorganic Hybrids Fabricated from Glucomannan by Chemical Modification with Alkoxysilane and Calcium Salt," J. Ceram. Soc. Japan, 116(1), 46-49 (2008).
• T. Miyazaki, H. Akita, E. Ishida, M. Ashizuka and C. Ohtsuki, "Synthesis of Bioactive Organic-inorganic Hybrids from Tetraisopropyl Titanate and Hydroxyethylmethacrylate," J. Ceram. Soc. Japan, 114(1), 87-91 (2006).
• T. Miyazaki, C. Ohtsuki and M. Tanihara, "Synthesis of Bioactive Organic-inorganic Nano-hybrid for Bone Repair through Sol-gel Processing" J. Nanosci. Nanotech., 3(6), 511-515 (2003).